Institute News
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Startup News - Clemedi incorporated
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New article: LTK releases article about the progress of transgenic techniques in the field of immunology
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LTK visits Central Animal Services at the Witwatersrand University in Johannesburg to present an introductory laboratory animal science workshop
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Our new teaching and training course registration system is now online and ready to use
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New publication: PD-1 is a haploinsufficient suppressor of T cell lymphomagenesis
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Tissue adaptation of regulatory and intraepithelial CD4⁺ T cells controls gut inflammation.
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New Publication: Roquin recognizes a non-canonical hexaloop structure in the 3′-UTR of Ox40, Nat. Com.
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New publication: Tumor-necrosis factor impairs CD4+ T cell-mediated immunological control in chronic viral infection, Nat. Immunol.
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New Publication: T cell-specific inactivation of mouse CD2 by CRISPR/Cas9, Scientific Reports
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We welcome our new lab members!
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New Publication: Fecal microbiota transfer (FMT) in a patient with refractory irritable bowel syndrome
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Fecal microbiota transfer (FMT) in a patient with refractory irritable bowel syndrome
Irritable bowel syndrome is a disorder of the gastrointestinal tract with unknown etiology. Recent clinical data support a link between changes in fecal microbiota with decreased biodiversity and the development of irritable bowel syndrome. Whether these changes of the microbiota are caused by the disease or whether they develop during the course of the disease remains unclear.Several studies demonstrated that fecal microbiota transfer (FMT) successfully attenuates Clostridium difficile infection by restoring the disturbed bacterial flora of the gut and case reports suggest that FMT may relief symptoms in patients with irritable bowel syndrome (IBS).Here we report a 47-year-old male patient with longstanding refractory diarrhea predominant IBS, who was successfully treated with a single FMT. The beneficial effect on the patient's symptoms was associated with changes of the stool microbiome. Post-FMT the recipient's microbiome resembled the donor´s microbiome. Zoller et al.; Dtsch Med Wochenschr. 2015 Aug;140(16):1232-6. Pubmed
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